The chemicals we use in everyday life may pose a risk to human health and the environment. As we learn more about their interactions, these emerging contaminants, such as PFAS (Per-and polyfluoroalkyl substances) and 1,4-Dioxane have gained world-wide attention. PFAS have been used in industrial applications and common consumer projects; 1,4-Dioxane is an industrial solvent. PFAS are found in thousands of fluorine-containing chemicals that are resistant to heat, water, and petroleum products. Studies suggest these emerging contaminants may affect different systems in the human body. Although research is ongoing, federal and state regulatory bodies have begun to develop policies and cleanup criteria for these components. We are currently monitoring the EPA’s designation of PFAS, including their salts and structural isomers, as hazardous substances under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), also known as Superfund.